Major depressive disorder. Psychopathology, medical management and dental implications.
Identifieur interne : 000509 ( Main/Exploration ); précédent : 000508; suivant : 000510Major depressive disorder. Psychopathology, medical management and dental implications.
Auteurs : A H Friedlander [États-Unis] ; M E MahlerSource :
- Journal of the American Dental Association (1939) [ 0002-8177 ] ; 2001.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen (MeSH), Affect (MeSH), Analgésiques (usage thérapeutique), Antidépresseurs (effets indésirables), Antidépresseurs (usage thérapeutique), Caries dentaires (étiologie), Cariostatiques (usage thérapeutique), Fatigue (physiopathologie), Femelle (MeSH), Fluorures (usage thérapeutique), Humains (MeSH), Hygiène buccodentaire (MeSH), Maladies parodontales (étiologie), Mâle (MeSH), Prévalence (MeSH), Qualité de vie (MeSH), Relations interpersonnelles (MeSH), Récidive (MeSH), Régime cariogène (MeSH), Salive (métabolisme), Salive artificielle (usage thérapeutique), Soins dentaires pour malades chroniques (MeSH), Suicide (MeSH), Sujet âgé (MeSH), Trouble dépressif (physiopathologie), Trouble dépressif (psychologie), Trouble dépressif (traitement médicamenteux), Troubles de la veille et du sommeil (physiopathologie), Troubles sensitifs (étiologie), Xérostomie (induit chimiquement), Éducation du patient comme sujet (MeSH).
- MESH :
- effets indésirables : Antidépresseurs.
- induit chimiquement : Xérostomie.
- métabolisme : Salive.
- physiopathologie : Fatigue, Trouble dépressif, Troubles de la veille et du sommeil.
- psychologie : Trouble dépressif.
- traitement médicamenteux : Trouble dépressif.
- usage thérapeutique : Analgésiques, Antidépresseurs, Cariostatiques, Fluorures, Salive artificielle.
- étiologie : Caries dentaires, Maladies parodontales, Troubles sensitifs.
- Adulte d'âge moyen, Affect, Femelle, Humains, Hygiène buccodentaire, Mâle, Prévalence, Qualité de vie, Relations interpersonnelles, Récidive, Régime cariogène, Soins dentaires pour malades chroniques, Suicide, Sujet âgé, Éducation du patient comme sujet.
English descriptors
- KwdEn :
- Affect (MeSH), Aged (MeSH), Analgesics (therapeutic use), Antidepressive Agents (adverse effects), Antidepressive Agents (therapeutic use), Cariostatic Agents (therapeutic use), Dental Care for Chronically Ill (MeSH), Dental Caries (etiology), Depressive Disorder (drug therapy), Depressive Disorder (physiopathology), Depressive Disorder (psychology), Diet, Cariogenic (MeSH), Fatigue (physiopathology), Female (MeSH), Fluorides (therapeutic use), Humans (MeSH), Interpersonal Relations (MeSH), Male (MeSH), Middle Aged (MeSH), Oral Hygiene (MeSH), Patient Education as Topic (MeSH), Periodontal Diseases (etiology), Prevalence (MeSH), Quality of Life (MeSH), Recurrence (MeSH), Saliva (metabolism), Saliva, Artificial (therapeutic use), Sensation Disorders (etiology), Sleep Wake Disorders (physiopathology), Suicide (MeSH), Xerostomia (chemically induced).
- MESH :
- chemical , adverse effects : Antidepressive Agents.
- chemical , therapeutic use : Analgesics, Antidepressive Agents, Cariostatic Agents, Fluorides, Saliva, Artificial.
- chemically induced : Xerostomia.
- drug therapy : Depressive Disorder.
- etiology : Dental Caries, Periodontal Diseases, Sensation Disorders.
- metabolism : Saliva.
- physiopathology : Depressive Disorder, Fatigue, Sleep Wake Disorders.
- psychology : Depressive Disorder.
- Affect, Aged, Dental Care for Chronically Ill, Diet, Cariogenic, Female, Humans, Interpersonal Relations, Male, Middle Aged, Oral Hygiene, Patient Education as Topic, Prevalence, Quality of Life, Recurrence, Suicide.
Abstract
BACKGROUND
Major depressive disorder, or MDD, is a psychiatric illness in which mood, thoughts and behavioral patterns are impaired for long periods. The illness distresses the person and impairs his or her social functioning and quality of life. MDD is characterized by marked sadness or a loss of interest or pleasure in daily activities, and is accompanied by weight change, sleep disturbance, fatigue, difficulty concentrating, physical impairment and a high suicide rate. In 2000, the World Health Organization, or WHO, identified MDD as the fourth ranked cause of disability and premature death in the world. WHO projected that by 2020, MDD would rise in disease burden to be second only to ischemic heart disease. The disorder is common in the United States, with a lifetime prevalence rate of 17 percent and a recurrence rate of more than 50 percent.
CONCLUSIONS
MDD may be associated with extensive dental disease, and people may seek dental treatment before becoming aware of their psychiatric illness. MDD frequently is associated with a disinterest in performing appropriate oral hygiene techniques, a cariogenic diet, diminished salivary flow, rampant dental caries, advanced periodontal disease and oral dysesthesias. Many medications used to treat the disease magnify the xerostomia and increase the incidence of dental disease. Appropriate dental management requires a vigorous dental education program, the use of saliva substitutes and anticaries agents containing fluoride, and special precautions when prescribing or administering analgesics and local anesthetics.
CLINICAL IMPLICATIONS
Dentists cognizant of these signs and symptoms have an opportunity to recognize patients with occult MDD. After confirmation of the diagnosis and institution of treatment by a mental health practitioner, dentists usually can provide a full range of services that may enhance patients' self-esteem and contribute to the psychotherapeutic aspect of management.
DOI: 10.14219/jada.archive.2001.0240
PubMed: 11367967
Affiliations:
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Psychopathology, medical management and dental implications.</title><author><name sortKey="Friedlander, A H" sort="Friedlander, A H" uniqKey="Friedlander A" first="A H" last="Friedlander">A H Friedlander</name><affiliation wicri:level="1"><nlm:affiliation>Veterans Affairs Greater Los Angeles Healthcare System (14), 11301 Wilshire Blvd., Los Angeles, Calif. 90073, USA. arthur.friedlander@med.va.gov</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Veterans Affairs Greater Los Angeles Healthcare System (14), 11301 Wilshire Blvd., Los Angeles, Calif. 90073</wicri:regionArea><wicri:noRegion>Calif. 90073</wicri:noRegion></affiliation></author><author><name sortKey="Mahler, M E" sort="Mahler, M E" uniqKey="Mahler M" first="M E" last="Mahler">M E Mahler</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2001">2001</date><idno type="RBID">pubmed:11367967</idno><idno type="pmid">11367967</idno><idno type="doi">10.14219/jada.archive.2001.0240</idno><idno type="wicri:Area/Main/Corpus">000519</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000519</idno><idno type="wicri:Area/Main/Curation">000519</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000519</idno><idno type="wicri:Area/Main/Exploration">000519</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Major depressive disorder. Psychopathology, medical management and dental implications.</title><author><name sortKey="Friedlander, A H" sort="Friedlander, A H" uniqKey="Friedlander A" first="A H" last="Friedlander">A H Friedlander</name><affiliation wicri:level="1"><nlm:affiliation>Veterans Affairs Greater Los Angeles Healthcare System (14), 11301 Wilshire Blvd., Los Angeles, Calif. 90073, USA. arthur.friedlander@med.va.gov</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Veterans Affairs Greater Los Angeles Healthcare System (14), 11301 Wilshire Blvd., Los Angeles, Calif. 90073</wicri:regionArea><wicri:noRegion>Calif. 90073</wicri:noRegion></affiliation></author><author><name sortKey="Mahler, M E" sort="Mahler, M E" uniqKey="Mahler M" first="M E" last="Mahler">M E Mahler</name></author></analytic><series><title level="j">Journal of the American Dental Association (1939)</title><idno type="ISSN">0002-8177</idno><imprint><date when="2001" 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(etiology)</term><term>Prevalence (MeSH)</term><term>Quality of Life (MeSH)</term><term>Recurrence (MeSH)</term><term>Saliva (metabolism)</term><term>Saliva, Artificial (therapeutic use)</term><term>Sensation Disorders (etiology)</term><term>Sleep Wake Disorders (physiopathology)</term><term>Suicide (MeSH)</term><term>Xerostomia (chemically induced)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen (MeSH)</term><term>Affect (MeSH)</term><term>Analgésiques (usage thérapeutique)</term><term>Antidépresseurs (effets indésirables)</term><term>Antidépresseurs (usage thérapeutique)</term><term>Caries dentaires (étiologie)</term><term>Cariostatiques (usage thérapeutique)</term><term>Fatigue (physiopathologie)</term><term>Femelle (MeSH)</term><term>Fluorures (usage thérapeutique)</term><term>Humains (MeSH)</term><term>Hygiène buccodentaire (MeSH)</term><term>Maladies parodontales (étiologie)</term><term>Mâle (MeSH)</term><term>Prévalence (MeSH)</term><term>Qualité de vie (MeSH)</term><term>Relations interpersonnelles (MeSH)</term><term>Récidive (MeSH)</term><term>Régime cariogène (MeSH)</term><term>Salive (métabolisme)</term><term>Salive artificielle (usage thérapeutique)</term><term>Soins dentaires pour malades chroniques (MeSH)</term><term>Suicide (MeSH)</term><term>Sujet âgé (MeSH)</term><term>Trouble dépressif (physiopathologie)</term><term>Trouble dépressif (psychologie)</term><term>Trouble dépressif (traitement médicamenteux)</term><term>Troubles de la veille et du sommeil (physiopathologie)</term><term>Troubles sensitifs (étiologie)</term><term>Xérostomie (induit chimiquement)</term><term>Éducation du patient comme sujet (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antidepressive Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Analgesics</term><term>Antidepressive Agents</term><term>Cariostatic Agents</term><term>Fluorides</term><term>Saliva, Artificial</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Xerostomia</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Depressive Disorder</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Antidépresseurs</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Dental Caries</term><term>Periodontal Diseases</term><term>Sensation Disorders</term></keywords><keywords scheme="MESH" qualifier="induit chimiquement" xml:lang="fr"><term>Xérostomie</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Salive</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Fatigue</term><term>Trouble dépressif</term><term>Troubles de la veille et du sommeil</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Depressive Disorder</term><term>Fatigue</term><term>Sleep Wake Disorders</term></keywords><keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Trouble dépressif</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Depressive Disorder</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Trouble dépressif</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Analgésiques</term><term>Antidépresseurs</term><term>Cariostatiques</term><term>Fluorures</term><term>Salive artificielle</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Caries dentaires</term><term>Maladies parodontales</term><term>Troubles sensitifs</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Affect</term><term>Aged</term><term>Dental Care for Chronically Ill</term><term>Diet, Cariogenic</term><term>Female</term><term>Humans</term><term>Interpersonal Relations</term><term>Male</term><term>Middle Aged</term><term>Oral Hygiene</term><term>Patient Education as Topic</term><term>Prevalence</term><term>Quality of Life</term><term>Recurrence</term><term>Suicide</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Affect</term><term>Femelle</term><term>Humains</term><term>Hygiène buccodentaire</term><term>Mâle</term><term>Prévalence</term><term>Qualité de vie</term><term>Relations interpersonnelles</term><term>Récidive</term><term>Régime cariogène</term><term>Soins dentaires pour malades chroniques</term><term>Suicide</term><term>Sujet âgé</term><term>Éducation du patient comme sujet</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Major depressive disorder, or MDD, is a psychiatric illness in which mood, thoughts and behavioral patterns are impaired for long periods. The illness distresses the person and impairs his or her social functioning and quality of life. MDD is characterized by marked sadness or a loss of interest or pleasure in daily activities, and is accompanied by weight change, sleep disturbance, fatigue, difficulty concentrating, physical impairment and a high suicide rate. In 2000, the World Health Organization, or WHO, identified MDD as the fourth ranked cause of disability and premature death in the world. WHO projected that by 2020, MDD would rise in disease burden to be second only to ischemic heart disease. The disorder is common in the United States, with a lifetime prevalence rate of 17 percent and a recurrence rate of more than 50 percent.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>MDD may be associated with extensive dental disease, and people may seek dental treatment before becoming aware of their psychiatric illness. MDD frequently is associated with a disinterest in performing appropriate oral hygiene techniques, a cariogenic diet, diminished salivary flow, rampant dental caries, advanced periodontal disease and oral dysesthesias. Many medications used to treat the disease magnify the xerostomia and increase the incidence of dental disease. Appropriate dental management requires a vigorous dental education program, the use of saliva substitutes and anticaries agents containing fluoride, and special precautions when prescribing or administering analgesics and local anesthetics.</p></div><div type="abstract" xml:lang="en"><p><b>CLINICAL IMPLICATIONS</b></p><p>Dentists cognizant of these signs and symptoms have an opportunity to recognize patients with occult MDD. After confirmation of the diagnosis and institution of treatment by a mental health practitioner, dentists usually can provide a full range of services that may enhance patients' self-esteem and contribute to the psychotherapeutic aspect of management.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">11367967</PMID><DateCompleted><Year>2001</Year><Month>07</Month><Day>26</Day></DateCompleted><DateRevised><Year>2019</Year><Month>07</Month><Day>09</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0002-8177</ISSN><JournalIssue CitedMedium="Print"><Volume>132</Volume><Issue>5</Issue><PubDate><Year>2001</Year><Month>May</Month></PubDate></JournalIssue><Title>Journal of the American Dental Association (1939)</Title><ISOAbbreviation>J Am Dent Assoc</ISOAbbreviation></Journal><ArticleTitle>Major depressive disorder. Psychopathology, medical management and dental implications.</ArticleTitle><Pagination><MedlinePgn>629-38</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Major depressive disorder, or MDD, is a psychiatric illness in which mood, thoughts and behavioral patterns are impaired for long periods. The illness distresses the person and impairs his or her social functioning and quality of life. MDD is characterized by marked sadness or a loss of interest or pleasure in daily activities, and is accompanied by weight change, sleep disturbance, fatigue, difficulty concentrating, physical impairment and a high suicide rate. In 2000, the World Health Organization, or WHO, identified MDD as the fourth ranked cause of disability and premature death in the world. WHO projected that by 2020, MDD would rise in disease burden to be second only to ischemic heart disease. The disorder is common in the United States, with a lifetime prevalence rate of 17 percent and a recurrence rate of more than 50 percent.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">MDD may be associated with extensive dental disease, and people may seek dental treatment before becoming aware of their psychiatric illness. MDD frequently is associated with a disinterest in performing appropriate oral hygiene techniques, a cariogenic diet, diminished salivary flow, rampant dental caries, advanced periodontal disease and oral dysesthesias. Many medications used to treat the disease magnify the xerostomia and increase the incidence of dental disease. Appropriate dental management requires a vigorous dental education program, the use of saliva substitutes and anticaries agents containing fluoride, and special precautions when prescribing or administering analgesics and local anesthetics.</AbstractText><AbstractText Label="CLINICAL IMPLICATIONS" NlmCategory="CONCLUSIONS">Dentists cognizant of these signs and symptoms have an opportunity to recognize patients with occult MDD. After confirmation of the diagnosis and institution of treatment by a mental health practitioner, dentists usually can provide a full range of services that may enhance patients' self-esteem and contribute to the psychotherapeutic aspect of management.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Friedlander</LastName><ForeName>A H</ForeName><Initials>AH</Initials><AffiliationInfo><Affiliation>Veterans Affairs Greater Los Angeles Healthcare System (14), 11301 Wilshire Blvd., Los Angeles, Calif. 90073, USA. arthur.friedlander@med.va.gov</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mahler</LastName><ForeName>M E</ForeName><Initials>ME</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Am Dent Assoc</MedlineTA><NlmUniqueID>7503060</NlmUniqueID><ISSNLinking>0002-8177</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000700">Analgesics</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000928">Antidepressive Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D002327">Cariostatic Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012464">Saliva, Artificial</NameOfSubstance></Chemical><Chemical><RegistryNumber>Q80VPU408O</RegistryNumber><NameOfSubstance UI="D005459">Fluorides</NameOfSubstance></Chemical></ChemicalList><CitationSubset>D</CitationSubset><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="ErratumIn"><RefSource>J Am Dent Assoc 2001 Jun;132(6):736</RefSource></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000339" MajorTopicYN="N">Affect</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000700" MajorTopicYN="N">Analgesics</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000928" MajorTopicYN="N">Antidepressive Agents</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002327" MajorTopicYN="N">Cariostatic Agents</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017742" MajorTopicYN="Y">Dental Care for Chronically Ill</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003731" MajorTopicYN="N">Dental Caries</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003866" MajorTopicYN="N">Depressive Disorder</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName><QualifierName UI="Q000523" MajorTopicYN="Y">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004037" MajorTopicYN="N">Diet, Cariogenic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005221" MajorTopicYN="N">Fatigue</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005459" MajorTopicYN="N">Fluorides</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007398" MajorTopicYN="N">Interpersonal Relations</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009910" MajorTopicYN="N">Oral Hygiene</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010353" MajorTopicYN="N">Patient Education as Topic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010510" MajorTopicYN="N">Periodontal Diseases</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011788" MajorTopicYN="N">Quality of Life</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012008" MajorTopicYN="N">Recurrence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012463" MajorTopicYN="N">Saliva</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012464" MajorTopicYN="N">Saliva, Artificial</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012678" MajorTopicYN="N">Sensation Disorders</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012893" MajorTopicYN="N">Sleep Wake Disorders</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013405" MajorTopicYN="N">Suicide</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014987" MajorTopicYN="N">Xerostomia</DescriptorName><QualifierName UI="Q000139" MajorTopicYN="N">chemically induced</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2001</Year><Month>5</Month><Day>23</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2001</Year><Month>7</Month><Day>28</Day><Hour>10</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2001</Year><Month>5</Month><Day>23</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">11367967</ArticleId><ArticleId IdType="pii">S0002-8177(14)61708-6</ArticleId><ArticleId 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